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Antifungal properties of Brazilian cerrado plants BJM
Souza,Lúcia Kioko Hasimoto e; Oliveira,Cecília Maria Alves de; Ferri,Pedro Henrique; Santos,Suzana Costa; Oliveira Júnior,Juldásio Galdino de; Miranda,André Thiago Borges; Lião,Luciano Morais; Silva,Maria do Rosário Rodrigues.
Ethanolic extracts from leaves of Hyptis ovalifolia, H. suaveolens, H. saxatilis, Hyptidendrum canum, Eugenia uniflora, E. dysenterica, Caryocar brasiliensis and Lafoensia pacari were investigated for their antifungal activity against dermatophytes. The most effective plants were H. ovalifolia and E. uniflora, while Trichophyton rubrum was the most sensitive among the four dermatophytes species evaluated. This study has demonstrated antifungal properties of Brazilian Cerrado plant extracts in "in vitro" assays.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dermatophytes; Antifungal activity; Plant extracts; Susceptibility tests.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822002000300012
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Drug resistance of yeasts isolated from oropharyngeal candidiasis in aids patients Rev. Microbiol.
Silva,Maria do Rosário Rodrigues; Paula,Claudete Rodrigues de; Silva,Soraya Cristina; Costa,Théo Rodrigues; Costa,Márcio Rodrigues.
Candida spp was isolated from 59 (68.60%) out of eighty six samples of oral mucosa of AIDS patients. The identification, based or the production of a germ tube and chlamydospores, and on the assimilation and fermentation of carbohydrates, revealed 52 strains (88.13%) of C. albicans, 4 (6.77%) of C. tropicalis and 3 (5.08%) of C. krusei. The susceptibility of these strains to amphotericin B, flucytosine, itraconazole, fluconazole and ketoconazole was determined using the agar dilution method. Comparing the minimum inhibitory concentration values found in the susceptibility test with the serum levels achieved by these drugs, only 8.47% and 5.08% of the yeasts strains proved to be resistant to amphotericin B and flucitosyne, respectively. A high frequency of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Oropharyngeal candidiasis; Yeasts; In vitro resistance; Antifungal drugs.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37141998000400007
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Susceptibility testing of Candida albicans isolated from oropharyngeal mucosa of HIV+ patients to fluconazole, amphotericin B and Caspofungin: killing kinetics of caspofungin and amphotericin B against fluconazole resistant and susceptible isolates BJM
Lemos,Janine de Aquino; Costa,Carolina Rodrigues; Araújo,Crystiane Rodrigues de; Souza,Lúcia Kioko Hasimoto e; Silva,Maria do Rosário Rodrigues.
A clear understanding of the pharmacodynamic properties of antifungal agents is important for the adequate treatment of fungal infections like candidiasis. For certain antifungal agents, the determination of Minimal Fungicidal Concentration (MFC) and time kill curve could be clinically more relevant than the determination of the Minimal Inhibitory Concentration (MIC). In this study, MIC and MFC to fluconazole, amphotericin B and caspofungin against C. albicans isolates and the killing patterns obtained with caspofungin and amphotericin B against susceptible and resistant strains to fluconazole were determined. The results of MICs showed that all C. albicans isolates were highly susceptible to amphotericin B, but two isolates were fluconazole resistant. The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antifungal susceptibility; Candida albicans; Time kill curves.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822009000100028
Registros recuperados: 3
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